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intercross-200

Summaries

High accuracy thermoregulation system with the Peltier element
It is various and evaluates somatic sensation by four functions

Thermal threshold Measurement

It measures the human thermal comfort threshold using the heat flux as an indicator.
It independently evaluates the warm and cold sensation in a short time.
It realizes a low speed thermoregulation of 0.1℃/sec by high accuracy.

Pain stimulation

Stimulate skin in thermostat rate of up to 15 ℃ /sec.
High- speed temperature control system with few overshoot.
The stimulation in the MRI is possible, too. (At the time of optional inserting.)

Threshold for pain sensation

It realizes the repetition of the warm and cold pain sensation at high repeatability.

Synchronization input unit

External synchronizing input 6ch.
1kHz sampling.
Brain waves, an electrocardiogram and blood flow sweat rate are measured with temperature stimulation by synchronization.

Analyze a threshold for warm and cold sense.

<Measurement screen>

flux


25mm square probe for heat


*Rationale for setting heat flux as an index of measurement.
Compared to temperature, heat flux is a more accurate reflection of thermal energy moving between substances.
For example, when we compare a metal and piece of wood on our skin, we feel that the metal is colder, even if both materials have the same exact temperature. This suggests that the perception of temperature is related to the flow of thermal energy between objects and skin, and not the actual temperature itself.
By setting the heat flux as an indicator, this enables the evaluation of absolute values which is not possible with a temperature index.

Threshold for pain sensation

It is high- precise control system at the time of awareness with few overshoot.
It sifts or reverses to the next stimulation smoothly.

Measure a threshold according to the difference of temperature.

<Setting screen>




30mmφprobe

■ Stimulation of pain sensation

Probe temperature changes according to a setting temperature program.

<Setting>

・Range of stimulating temperature:
 -10℃~50℃(limited by a limiter function)
・Thermoregulation speed:
 0.1~15℃/sec
・Thermoregulation sequence segment number:
 Maximum 100 segment


10mm square water-cooled probe

<MRI unit>
This external unit is designed to prevent noise from mixing into the received signal of MRI.

 Probe for MRI

Probes

【For Human】


Air-cooled 25mm square probe for heat flux


10mm square probe


Probe for intraoral


10mm square probe for face


Probe for MRI


30mmφwith hole for Blood Flow

【For Animal】


1mmφ


3mm square

Specifications

■intercross-210
A temperature sensor
-60℃~60℃
Heat flux sensor
±10000W/m2
Range for temperature control
-10℃~50℃
Thermoregulation speed for probe
0.1 ℃/sec ~15℃/sec
Sampling frequency 
1Hz  10Hz  100Hz  500Hz  512Hz

1000Hz  1024Hz   (possible alternative)
Input channel 8ch
1ch: Probe temperature

2ch: Heat flux of probe

3ch~8ch: Option
Input range ±10V
Thermoregulation method Peltier element
Output USB
Power supply AC100V  50/60Hz
Configuration 350mm×300mm×70mm
Weight 5kg

Attachment
Power cable
intercross-210-01
Event switch  intercross-210-02
USB cable intercross-210-04





Option
4 analog input cable set
intercross-210-03
MRI unit
intercross-210-05
Pump unit for water-cooled probe intercross-210-06
Software
Measuring software for threshold of warm and cold sense : intercross-210-51
<Measurement condition setting items>
Thermoregulation mode
Temperature mode, Heat flux mode,
  Double-blind mode
Starting temperature designation
Temperature or Heat flux
Thermoregulation speed
0.1℃/sec  0.3℃/sec  0.5℃/sec  (Select)
Thermoregulation direction
Heating or Cooling
Result list
Starting temperature, Awareness temperature,
  Awareness temperature difference,

Awareness time, Starting heat flux,

Awareness heat flux,
  Awareness heat flux difference

Integral value of the heat flux
The number of the display channel Maximum 8 channel
Weight 5kg

Software for stimulation of pain sensation : intercross-210-53
<Thermoregulation setting item>
Designated range for stimulation temperature
-10℃~50℃
Stimulating thermoregulation speed 0.1℃/sec ~15℃/sec
Designation for stimulating time
0.1 sec ~ 300sec
Programmable number of segment
100

Maximum and minimum thermoregulation
The number of the display channel Maximum 8 channel

Program for stimulation of pain sensation : intercross-210-52
<Thermoregulation setting item>
A basement temperature or basement heat flux
(Designation optionally)
Thermoregulation speed 0.1℃/sec~5℃/sec  (Designation optionally)
The number of thermoregulation repetition
1 ~20times  (Designation optionally)
The initial thermoregulation direction
Heating or Cooling (Select)
Result list
Skin temperature at the time of awareness
Average value of skin temperature at the time of awareness
Standard deviation value of skin temperature at the time of awareness
Maximum value of skin temperature at the time of awareness
Minimum value of skin temperature at the time of awarenes
The number of the display channel Maximum 8 channel
Configuration of intercross-210 system

Threshold for warm and cold sense   Stimulation of pain Stimulation of pain for MRI Threshold for pain sense

intercross-210 
Probe 25mmsquare
water-cooled with heat flux
10mm square
Water-cooled
10mm square
Water-cooled for MRI
30mmφ
With bloodstream hole 
software
Intercross-210-51  Intercross-210-53
Intercross-210-53 Intercross-210-52
other
  Pump unit for water-cooled probe Pump unit for water-cooled probe
MRI unit
Pump unit for water-cooled probe

Reference List

Main literature list

Accuracy and reliability of threshold measurement in the chin using heat flux technique
Teppei Kawano,Yuhji Kabasawa,Suga Ashikawa,Yuriko Sato,Shigeharu Jinno,Ken Omura OOOOE Vol.108,No.4 October 2009
Measuring heat flux and amount of heat as indexes of cold pain threshold
Kazuhiro Shimo,Shigeyuki Suzuki,Takahiro Ushida PAIN RESEARCH 27(2012)17-26
Cutaneous Warm and Cool Sensation Thresholds and the Inter-threshold Zone in Malaysian and Japanese Males 
Joo-Young Lee,Mohamed Saat,Chinmei Chou,Nobuko Hashiguchi,Titis Wijayanto,Hitoshi Wakabayashi,Yutaka Toshihara Journal of Thermal Biology 2009
A new evaluation method for neurosensory disturbance in the chin of patients undergoing mandibular sagittal split ramus osteotomy:an application of the heat flux technique
Yuhji Kabasawa,Kiyoshi Harada,Shigeharu Jinno,Yuriko Satoh,Yutaka Maruoka,Ken Omura OOOOE Vol.102,No.6 December 2006
Changes in Cold/Warm Thresholds with Advancing Age―The Case of Adult Women Aged from the 20s to the 80s―
Yukiko Uchida,Teruko Tamura,Fusako Iwasaki SEN'I GAKKAISHI(報文) Vol.65,No.5(2009)
Peripheral Warm and Cool Thresholds in Malaysian and Japanese Males
Joo-Young LEE,Mohamed SAAT,Chin-Mei CHOU,Titis WIJAYANTO,Hitoshi WAKABAYASHI,Yutaka TOCHIHARA 日本生理人類学会誌 Vol.14特別号 第60回大会要旨集(北海道 2009年6月)
Age-related differences in cutaneous warm sensation thresholds of human males in thermoneutral and cool environments
Yutaka Tochihara,Teruyuki Kumamoto,Joo-Young Lee,Nobuko Hashiguchi Journal of Thermal Biology36(2011)105–111
cold/warm thresholds,skin temperature and skin blood flow waves in young women with cold constitutions(hie-sho)
Mariko Sato,Teruko Tamura ICB2008,Clothing,Poster

Patent

Patent number. 3888749

Using electrical physiology measurements to assess/analyse to a person state and reactions to stimuli.


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